Siloxia, a versatile pharmaceutical silica platform
We Master Pharmaceutical Silica Solutions.
Siloxia is a pharmaceutical silica-based technology service platform that opens up many possibilities for an increased active pharmaceutical ingredient (API) and formulation performance. Mesoporous silica is a very versatile product that can be used in a large number of pharmaceutical applications such as active pharmaceutical ingredient carrier, SEDDS systems, suspensions, moisture protection, controlled release and process related parameters like tableting glidant and disintegration aid. It can be applied for both hydrophilic and hydrophobic API’s.
Especially in cases where the active pharmaceutical ingredient faces certain limitations like lipid nature, liquisolid, oil, polymorphic changes, limited solubility or instability, mesoporous silica can be a straight-forward solution to overcome these challenges.
Mesoporous silica consist of small particles containing predefined pores creating a very large surface area in which the active pharmaceutical ingredient can be absorbed. Solvent impregnation is a well-known technique to incorporate active pharmaceutical ingredient in silica pores, Siloxia also offers the possibility to load pores without the use of solvents by using a dry loading technology.
Safe, robust and stable pharmaceutical products
Siloxia offers fast and flexible hands-on mesoporous silica solutions and troubleshooting services for pharmaceutical drug companies that are facing challenges like:
– active pharmaceutical ingredient morphology
– active pharmaceutical ingredient stability
– active pharmaceutical ingredient solubility
– active pharmaceutical ingredient availability
– Moisture protection
– Tabletting aid
– Controlled release
– and so on…
Siloxia, a division of Avivia BV
Siloxia as dedicated pharmaceutical silica knowledge platform is a division of Avivia BV, a Dutch independent specialized pharmaceutical development company that operates a hybrid business model combining CRO service activities with internal product development programs. The other complementary platforms of Avivia are Pharmaceutical R&D, Analytical R&D, Biorelevant Dissolution Testing and Excipient Characterization Excipia. For more information about Avivia and its pharmaceutical development CRO services, please visit the Avivia website.
Siloxia would be happy to learn more about your questions, please feel free to contact us.
Let’s absorb your challenges !
Transistorweg 5, 6534 AT Nijmegen, The Netherlands